Ailment: Crushing Injury

Site: Ankle

Synopsis: 44-year-old male sustained a crushing injury to his right ankle, while working under a car. The patient has undergone five surgeries to repair bones, bury nerves and re-attach tendons. He had also undergone several courses of physical therapy and three Cortisone injections into the right ankle. For his pain, which he described as "a constant ache with spasm and throbbing," he had been prescribed a couple different pain medications, including oral narcotics. He did not care for these because he could not function while on them.

Subsequently, the patient was prescribed a transdermal gel containing Ketamine, Gabapentin, Clonidine, Amitriptyline, and EMLA. The patient was instructed to apply the gel to the affected area 2-4 times daily. Follow-up phone conversation two weeks later revealed that the patient was getting relief within 5 minutes after applying the gel. Relief would last for several hours.

On a typical day, using the Pain Assessment Scale,* patient rates his initial pain level at 10. Within 5 minutes after application of the gel, his pain level is reduced to between 4 and 5. Within an hour or so, his pain level is further reduced to 1.

*Pain Assessment Scale: l=normal, 10=unbearable

Patient stated: This gel is wonderful!

Ailment: Multiple Back Problems

Site: Back

Synopsis: 35-year-old female with a past history of vertebral fracture (L5), arthritis, six bulging discs (3 cervical and 3 lumbar), scoliosis and arachnoiditis. She had been to several different physicians, who prescribed several different pain treatment modalities including: 5 epidurals, Cortisone injections into the spasmodic area (11 injections each time), oral narcotics, muscle relaxors, biofeedback and physical therapy. Her pain management physician prescribed a transdermal gel containing Ketoprofen and Cyclobenzaprine in treatment of her back pain. She reported that she obtained relief within a few minutes after the gel was applied. This relief lasted 2-6 hours, depending on her activity level. According to the Pain Assessment Scale,* she rated her pain level at 7 constantly (although there were times when it reached 10). From a level of 7, her pain level decreased to 4-5 within a few minutes of gel application. Use of the gel enabled her to again perform her daily-l iving activities.

*Pain Assessment Scale: l=normal, 10=unbearable

Patient stated: I love it and wouldn't be without it! The gel really calms down the spasm! ... Helps me get through the day.

Ailment: Post Herpetic Neuralgia

Site: chest and axilla

Synopsis: 65-year-old male had an outbreak of Herpes Zoster. A few weeks later, he developed post herpetic neuralgia involving the right side of his chest and right axilla. He rated his pain level up around 10 at this time. His treatment consisted of multiple oral pain medications and topical creams and ointments. These all offered some pain relief, but he found it very difficult to accomplish everyday activities while on oral narcotics. His pain management physician then prescribed a 5-ingredient transdermal gel consisting of Ketamine, Gabapentin, Clonidine, Amitriptyline, and EMLA to be applied to the affected areas 2-4 times daily. " Patient reported obtaining relief immediately after applying the gel. This relief lasted for a couple of hours. According to the Pain Assessment Scale,* patient rated his initial pain level around 10. After application of the gel, his pain level was reduced to level 5.

*Pain Assessment Scale: l=normal, 10=unbearable

Patient stated: This is the best thing I have ever used so far. It's very good!... Has helped me achieve a tolerable pain level where I can function normally.

Ailment: Musculoskeletal Injury

Site: Wrist

Synopsis: 64-year-old female suffered soft tissue injury to her right wrist when she slammed her wrist into the corner of her desk at work. She described her pain as a constant, throbbing-type pain that was very tender to touch. She had very limited mobility in the wrist joint. She saw a physician who prescribed a transdermal gel formula that consists of Ketamine, Ibuprofen, Dexamethasone and Lidocaine. She was instructed to apply this gel to her right wrist 3-4 times a day. The patient's pain level at the time of the accident was rated approximately 7 on the Pain Assessment Scale.* Within the first few applications of the gel, the patient was feeling much better, reporting relief obtained within 30 minutes after the first application, reducing here pain level to 4, with relief lasting a couple of hours. Follow up one month later ascertained that the patient was again able to play tennis without any problem. She still had some mild pain (pain level 2), however it was completely resolved with an application of the transdermal gel formula.

*Pain Assessment Scale: l=normal, 10=unbearable

Patient stated: It's working very well!

Ailment: Neuropathy (possible diabetic neuropathy)

Site: feet

Synopsis: 68-year-old female had experienced sudden bilateral foot pain 13 years earlier. She stated that her pain was so bad that she could not even walk. Over the years, she had seen a few physicians, including a chiropractor, for her condition. She was prescribed many different forms of treatment, including pain medications (Darvocet), anti-depressants, and nerve blocks. All of these were helpful for a short period of time. Ultimately, at a time when she was experiencing a pain level of 10, she was referred to a physician specializing in pain management. A transdermal gel consisting of Ketamine 15% and Lidocaine 5% was prescribed, to be applied sparingly to the affected area 2-4 times daily. Patient reported obtaining relief within 10-15 minutes of applying the Gel, with this relief lasting 3-4 hours with each application, reducing the pain level to 1 on the Pain Assessment Scale.

*Pain Assessment Scale: l=normal, 10=unbearable

Patient stated: This gel is wonderful! It really takes the burning right down! I wish I had known about this a long time ago.... This really helps me sleep through the night!